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Gene T Yocum Selected Research

MIDD0301

1/2022Comparative pharmacodynamic and pharmacokinetic study of MIDD0301 and its (S) enantiomer.
12/2020Nebulized MIDD0301 Reduces Airway Hyperresponsiveness in Moderate and Severe Murine Asthma Models.
1/2019A novel GABAA receptor ligand MIDD0301 with limited blood-brain barrier penetration relaxes airway smooth muscle ex vivo and in vivo.
1/2018A Novel Orally Available Asthma Drug Candidate That Reduces Smooth Muscle Constriction and Inflammation by Targeting GABAA Receptors in the Lung.

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Gene T Yocum Research Topics

Disease

13Asthma (Bronchial Asthma)
10/2022 - 01/2016
6Inflammation (Inflammations)
01/2022 - 01/2017
5Pneumonia (Pneumonitis)
02/2022 - 01/2020
5Respiratory Hypersensitivity
02/2022 - 01/2016
2Bronchial Spasm
12/2020 - 01/2020
2Cognitive Dysfunction
04/2010 - 05/2009
1Respiratory Insufficiency (Respiratory Failure)
12/2020
1Cystic Fibrosis (Mucoviscidosis)
01/2020
1Cough
01/2017
1Glioma (Gliomas)
03/2006
1Neoplasms (Cancer)
03/2006

Drug/Important Bio-Agent (IBA)

8Pharmaceutical PreparationsIBA
10/2022 - 01/2016
4MIDD0301IBA
01/2022 - 01/2018
4OvalbuminIBA
12/2020 - 01/2016
3LipopolysaccharidesIBA
02/2022 - 12/2020
3Methacholine Chloride (Methacholine)FDA Link
12/2020 - 01/2017
3LigandsIBA
01/2018 - 01/2017
2SteroidsIBA
02/2022 - 12/2020
2Albuterol (Salbutamol)FDA LinkGeneric
02/2022 - 12/2020
2AntigensIBA
09/2020 - 01/2020
1InterferonsIBA
01/2022
1Fluticasone (Cutivate)FDA LinkGeneric
12/2020
1AllergensIBA
12/2020
1Interferon-gamma (Interferon, gamma)IBA
12/2020
1CytokinesIBA
09/2020
1GelsolinIBA
09/2020
1Proteins (Proteins, Gene)FDA Link
09/2020
1Chemotactic FactorsIBA
09/2020
1ginger extractIBA
01/2020
1BenzbromaroneIBA
01/2020
1shogaolIBA
01/2020
1(3,4,5- trimethoxy- N- (2- methoxyethyl)- N- (4- phenyl- 2- thiazolyl)benzamideIBA
01/2020
1IsotopesIBA
01/2017
1CationsIBA
01/2017
1AerosolsIBA
01/2016
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
05/2009
1Protamines (Protamine Sulfate)FDA Link
03/2006
1erucylphosphocholineIBA
03/2006

Therapy/Procedure

2Oral Administration
01/2022 - 01/2018
2Therapeutics
01/2020 - 01/2016
2Carotid Endarterectomy
04/2010 - 05/2009